Flying into La Crosse, WI your first stop is likely to be at Colgan Air Services (www.colgan-air.com; 800-658-9498) to fuel up, tie-down, and rent a car. If you are just in for the day, ask to use the crew car for your drive to downtown.
The Midway Hotel Riverfront Resort (608-781-7000) is a good bet for those with children or if you want to plan a fishing excursion. Kids will enjoy the indoor pools complete with water slides. The hotel often sets up fishing trips on the adjacent Mississippi. Phone ahead to ensure your desired activity will be available.
If you visit during the winter, Mt. La Crosse (www.mtlacrosse.com; 800-426-3665) offering 18 ski and snowboard trails is a short drive to the South.
Anytime of year, visiting the historic Old Town is a treat. Lounge at one of the many coffee shops, hunt through the antique stores or eat at the various restaurants. If you are staying overnight, you can choose from a Courtyard, Radisson or Holiday Inn right in Old Town.